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Carmustine

(Synonyms: BCNU)
11 Cited Publications
Revisión del cliente

Based on 11 publication(s) in Google Scholar

Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.91%
  • No. CAS: 154-93-8
  • Fòrmula: C5H9Cl2N3O2
  • Peso molecular:214.05
  • Almacenamiento:

    -20°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Carmustine Chemical Structure
    Carmustine Chemical Structure
  • Experimental Validation Results for Carmustine
  • Experimental Validation Results for Carmustine
  • Experimental Validation Results for Carmustine
  • Experimental Validation Results for Carmustine
  • Experimental Validation Results for Carmustine
No. CAS: 154-93-8
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[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Flow CytometryCell Proliferation/Viability AssayIn Vivo Efficacy StudyCell Imaging/Staining
  • Cell Proliferation/Viability Assay
  • In Vivo Efficacy Study
  • Cell Imaging/Staining
  • Flow Cytometry
  • Cell Proliferation/Viability Assay
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  • Carmustine Chemical Structure
    Carmustine Chemical Structure
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    Carmustine purchased from MedChemExpress. Usage Cited in: Cancer Sci. 2026 Mar;117(3):695-710. [Abstract]

    Customer Validation
     RV increases the sensitivity of GBM cells to chemotherapeutic agents. Graphs show GBM cell viability after 48 h treatment with 50 μM RV combined with 50 μM TMZ or 50 μM Carmustine (BCNU), compared to DMSO and untreated controls (Ctrl).

  • 1/16

    Carmustine purchased from MedChemExpress. Usage Cited in: Nat Cell Biol. 2024 Sep;26(9):1545-1557. [Abstract]

    Customer Validation
     C57BL/6J mice bearing GSDME-overexpressing murine melanoma B16 cell-derived xenografts were treated intraperitoneally with Carmustine (20 mg/kg) and RSL3 (10 mg/kg) daily for 1 week. Xenograft tumours and their corresponding tumour weights are indicated (n = 7). PBS was used as a control. The results demonstrated that the combination of Carmustine and RSL3 effectively suppressed tumor growth.

  • 1/16

    Carmustine purchased from MedChemExpress. Usage Cited in: Nat Cell Biol. 2024 Sep;26(9):1545-1557. [Abstract]

    Customer Validation
     RSL3 (100 nM) combined with different reagents, including MMS (methyl methanesulfonate, 1 mM), MNNG (N-methyl-N’-nitro-N’-nitrosoguanidine, 0.3 mM) and Carmustine (0.25 mM)), were used to treated cells, the pyroptotic morphologies were observed. RSL3 combined with lower dose of UVC irradiation (50 mJ cm-2) was used as a positive control.

  • 1/16

    Carmustine purchased from MedChemExpress. Usage Cited in: Biomaterials. 2022 May;284:121533. [Abstract]

    Customer Validation
     Quantitative analysis of intracellular GSH using flow cytometry. Carmustine was used as positive control. ROS and GSH analysis were performed with 4T1 cells upon treatment for 6 h.

  • 1/16

    Carmustine purchased from MedChemExpress. Usage Cited in: J Drug Deliv Sci Technol. 9 September 2022, 103770.

    Customer Validation
     Dose response curves of free drugs and drug-loaded nanoparticles. In vitro cell viability assays of U251 cells after 48 h of incubation with Carmustine (BCNU, 62.5-500 μM), BCNU-loaded Fe3O4@MIL-88B–NH2 nanocomposites.

  • Carmustine