Vc-MMAD
Based on 1 Customer Validation
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a agent-linker conjugate for ADC.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.79%
- No. CAS: 1401963-17-4
- Fòrmula: C70H104N12O14S
- Peso molecular:1369.71
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1401963-17-4
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Appearance Solid
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Peso molecular 1369.71
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Fòrmula C70H104N12O14S
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Color White to off-white
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SMILES
O=C1N(CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N([C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N3[C@@H](CCC3)[C@H](OC)[C@H](C(N[C@H](C4=NC=CS4)CC5=CC=CC=C5)=O)C)=O)OC)[C@@H](C)CC)C)=O)=O)C)=O)C=C2)=O)=O)=O)C(C=C1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : ≥ 160 mg/mL (116.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7301 mL | 3.6504 mL | 7.3008 mL | 18.2520 mL |
| 5 mM | 0.1460 mL | 0.7301 mL | 1.4602 mL | 3.6504 mL | |
| 10 mM | 0.0730 mL | 0.3650 mL | 0.7301 mL | 1.8252 mL | |
| 15 mM | 0.0487 mL | 0.2434 mL | 0.4867 mL | 1.2168 mL | |
| 20 mM | 0.0365 mL | 0.1825 mL | 0.3650 mL | 0.9126 mL | |
| 25 mM | 0.0292 mL | 0.1460 mL | 0.2920 mL | 0.7301 mL | |
| 30 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6084 mL | |
| 40 mM | 0.0183 mL | 0.0913 mL | 0.1825 mL | 0.4563 mL | |
| 50 mM | 0.0146 mL | 0.0730 mL | 0.1460 mL | 0.3650 mL | |
| 60 mM | 0.0122 mL | 0.0608 mL | 0.1217 mL | 0.3042 mL | |
| 80 mM | 0.0091 mL | 0.0456 mL | 0.0913 mL | 0.2282 mL | |
| 100 mM | 0.0073 mL | 0.0365 mL | 0.0730 mL | 0.1825 mL |
Vc-MMAD Related Classifications
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