Adenallene
Adenallene, a nucleoside analogue, is an anti-HIV compound. Adenallene inhibits replication and cytopathic effect of HIV-1 and HIV-2.
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- No. CAS: 114987-18-7
- Fòrmula: C9H9N5O
- Peso molecular:203.20
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| ATH-8 cell line | EC50 |
14 μM
Compound: 1a
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Compound was evaluated for the inhibition of replication and cytopathic effect of HIV-1 in ATH8 cells
Compound was evaluated for the inhibition of replication and cytopathic effect of HIV-1 in ATH8 cells
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[PMID: 8765513] |
| ATH-8 cell line | IC50 |
3 μM
Compound: 3a
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Compound was evaluated for the inhibition of infectivity and cytopathic effect of HIV-1 in ATH8 cells
Compound was evaluated for the inhibition of infectivity and cytopathic effect of HIV-1 in ATH8 cells
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[PMID: 8765513] |
| CEM-SS | CC50 |
>100 μM
Compound: (+/-) Adenallene
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Cytotoxic concentration required to inhibit the replication of HIV-1 in CEM-SS human T4 lymphoblastoid cell lines
Cytotoxic concentration required to inhibit the replication of HIV-1 in CEM-SS human T4 lymphoblastoid cell lines
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[PMID: 11755368] |
| CEM-SS | EC50 |
56 μM
Compound: (+/-) Adenallene
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Effective concentration required to inhibit the replication of HIV-1 in CEMSS human T4 lymphoblastoid cell lines
Effective concentration required to inhibit the replication of HIV-1 in CEMSS human T4 lymphoblastoid cell lines
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[PMID: 11755368] |
| L1210 | IC50 |
150 μM
Compound: 5a
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Inhibitory activity against murine leukemia L1210 cells
Inhibitory activity against murine leukemia L1210 cells
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[PMID: 1992143] |
| MT2 | CC50 |
>100 μM
Compound: (+/-) Adenallene
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Cytotoxic concentration required to inhibit the replication of HIV-1 in MT-2 human T4 lymphoblastoid cell lines
Cytotoxic concentration required to inhibit the replication of HIV-1 in MT-2 human T4 lymphoblastoid cell lines
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[PMID: 11755368] |
| MT2 | EC50 |
>100 μM
Compound: (+/-) Adenallene
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Effective concentration required to inhibit the replication of HIV-1 in MT-2 human T4 lymphoblastoid cell lines
Effective concentration required to inhibit the replication of HIV-1 in MT-2 human T4 lymphoblastoid cell lines
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[PMID: 11755368] |
| MT4 | CC50 |
>100 μM
Compound: (+/-) Adenallene
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Cytotoxic concentration required to inhibit the replication of HIV-1 in MT-4 human T4 lymphoblastoid cell lines
Cytotoxic concentration required to inhibit the replication of HIV-1 in MT-4 human T4 lymphoblastoid cell lines
|
[PMID: 11755368] |
| MT4 | EC50 |
>100 μM
Compound: (+/-) Adenallene
|
Effective concentration required to inhibit the replication of HIV-1 in MT-4 human T4 lymphoblastoid cell lines
Effective concentration required to inhibit the replication of HIV-1 in MT-4 human T4 lymphoblastoid cell lines
|
[PMID: 11755368] |
Chemical Information
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No. CAS 114987-18-7
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Peso molecular 203.20
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Fòrmula C9H9N5O
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SMILES
OCC=C=CN1C=NC2=C(N=CN=C12)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Adenallene Related Classifications
HY-114731 Related Classifications
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