Alginic acid
Based on 1 publication(s) in Google Scholar
Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties.
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- Pureza : 97.0%
- No. CAS: 9005-32-7
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Alginic acid
MoreVer todos los productos específicos de isoformas Histamine Receptor
MoreVer todos los productos específicos de isoformas Endogenous Metabolite
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Actividad biológica
Descripciòn
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Alginic acid (AA) is a kind of polysaccharide extracted from brown seaweeds and has been widely used in food industry[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- Annexin V plus membrane-impermeant dye apoptosis staining
- ROS/oxidative-stress fluorescent staining
- Research Protocol for Endocrine Diseases
- Autophagy
- Apoptosis Solutions
- Lysosome and acidic-vesicle live-cell staining
- Research Protocol for Inflammation-related Diseases
- Macroautophagy Solutions
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 9005-32-7
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Appearance Solid
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Color White to off-white
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SMILES
O=C(O)[C@@H]1[C@@H](OC)[C@H](O)[C@H](O)[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O[C@H]2C(O)=O)OC)O1.[n]
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Structure Classification
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Initial Source
Macrocystis pyrifera
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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BMC Cancer
Targeting INF2 with DiosMetin 7-O-β-D-Glucuronide: a new stratagem for colorectal cancer therapy. [Abstract]2025 Jun 1;25(1):982. PMID: 40452021
Solvente y solubilidad
In Vitro:
H2O : 3.03 mg/mL (ultrasonic and adjust pH to 12 with 1M NaOH)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628. [Content Brief]
[2]. Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099. [Content Brief]
[3]. Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36(6):785-794. [Content Brief]
Alginic acid Related Classifications
HY-W127758 Related Classifications
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