ALLO-647
ALLO-647 is a human monoclonal antibody targeting CD52. ALLO-647 transiently and selectively depletes host lymphocytes to promote the proliferation of allogeneic CAR T-cell following infusion. ALLO-647 can be used for the research of B-cell lymphoma and follicular lymphoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Human
ALLO-647 is a human monoclonal antibody targeting CD52, a GPI-anchored low-molecular-weight glycoprotein that is highly expressed on almost all mature T and B cells but not on hematopoietic stem cells. Soluble CD52 is a natural inhibitor of the NF‑κB pathway, which mainly functions in myeloid cells and also exerts cross-regulation in T/B cells.[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CD52
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALLO-647 Related Classifications
HY-P992178 Related Classifications
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