Alsevalimab
Based on 1 publication(s) in Google Scholar
Alsevalimab is a humanized afucosylated IgG1 monoclonal antibody directed against B7-H4. Alsevalimab can be used for the research of advanced solid tumors.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : ≥95.0%
- No. CAS: 2254029-91-7
- Peso molecular:144.74 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Alsevalimab
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Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
B7-H4/VTCN1
In Vitro
Alsevalimab can be used alone or in combination with Pembrolizumab (HY-P9902) for tumor research[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG1 kappa
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Flow cytometric analysis of 1X106 Jurkat cells with Alsevalimab (HY-P99242, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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No. CAS 2254029-91-7
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Appearance Liquid
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Peso molecular 144.74 kDa
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Color Colorless to light yellow
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SMILES
[Alsevalimab]
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)