AM-4668
AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.0%
- No. CAS: 1011531-27-3
- Fòrmula: C24H19F3N2O4S
- Peso molecular:488.48
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Help & FAQs
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Fasiglifam (Standard)Reference Standard -
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DC260126 (Standard)Reference Standard -
HY-13967A
AMG 837 sodium saltGPR40/FFA1 Agonist -
HY-112603
AP5GPR40 Receptor Agonist
Actividad biológica
Descripciòn
IC50 & Target
EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| A9 | EC50 |
3.6 nM
Compound: 10, AM-4668
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Agonist activity at human GPR40 expressed in mouse A9 cells by inositol phosphate accumulation assay
Agonist activity at human GPR40 expressed in mouse A9 cells by inositol phosphate accumulation assay
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[PMID: 24900872] |
| CHO | EC50 |
36 nM
Compound: 10, AM-4668
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Agonist activity at human GPR40 expressed in CHO cells by aequorin assay
Agonist activity at human GPR40 expressed in CHO cells by aequorin assay
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[PMID: 24900872] |
Chemical Information
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No. CAS 1011531-27-3
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Appearance Solid
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Peso molecular 488.48
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Fòrmula C24H19F3N2O4S
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Color White to off-white
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SMILES
OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AM-4668 Related Classifications
HY-12585 Related Classifications
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