Ambroxide
Based on 1 Customer Validation
Ambroxide is a naturally occurring terpenoid. Ambroxide is one of the key constituents of ambergris. Ambroxide is used in the manufacture of high-end perfumes to improve the aroma quality and fragrance lasting time of perfumes.
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- Pureza : 98.0%
- No. CAS: 6790-58-5
- Fòrmula: C16H28O
- Peso molecular:236.39
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
Ambroxide serves as a substitute for natural ambergris, with ambery, woody smell reminiscent of tobacco and clary sage, produced via engineered yeast-fungus co-culture, zeolite conversion, or farnesene-based chemical-enzymatic routes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 6790-58-5
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Appearance Solid
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Peso molecular 236.39
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Fòrmula C16H28O
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Color White to off-white
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SMILES
C[C@]12CCCC(C)(C)[C@]1([H])CC[C@@]3(C)OCC[C@@]32[H]
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (105.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (10.58 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (278 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.2303 mL | 21.1515 mL | 42.3030 mL | 105.7574 mL |
| 5 mM | 0.8461 mL | 4.2303 mL | 8.4606 mL | 21.1515 mL | |
| 10 mM | 0.4230 mL | 2.1151 mL | 4.2303 mL | 10.5757 mL | |
| 15 mM | 0.2820 mL | 1.4101 mL | 2.8202 mL | 7.0505 mL | |
| 20 mM | 0.2115 mL | 1.0576 mL | 2.1151 mL | 5.2879 mL | |
| 25 mM | 0.1692 mL | 0.8461 mL | 1.6921 mL | 4.2303 mL | |
| 30 mM | 0.1410 mL | 0.7050 mL | 1.4101 mL | 3.5252 mL | |
| 40 mM | 0.1058 mL | 0.5288 mL | 1.0576 mL | 2.6439 mL | |
| 50 mM | 0.0846 mL | 0.4230 mL | 0.8461 mL | 2.1151 mL | |
| 60 mM | 0.0705 mL | 0.3525 mL | 0.7050 mL | 1.7626 mL | |
| 80 mM | 0.0529 mL | 0.2644 mL | 0.5288 mL | 1.3220 mL | |
| 100 mM | 0.0423 mL | 0.2115 mL | 0.4230 mL | 1.0576 mL |
Ambroxide Related Classifications
HY-N1384 Related Classifications
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