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Referencia número: HY-169481

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AP-1

Revisión del cliente

Based on 1 Customer Validation

AP-1 is a PROTAC targeting anaplastic lymphoma kinase (ALK).
(Pink: Anaplastic lymphoma kinase (ALK) ligand (HY-169482); Blue: Cereblon ligand (HY-10984); Black: linker).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 97.8%
No. CAS: 3027918-96-0
Fòrmula: C₃₉H₄₀ClN₉O₈S
Peso molecular:830.31

Almacenamiento:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

AP-1 Chemical Structure

No. CAS: 3027918-96-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

AP-1 is a PROTAC targeting anaplastic lymphoma kinase (ALK)^[1]. (Pink: Anaplastic lymphoma kinase (ALK) ligand (HY-169482); Blue: Cereblon ligand (HY-10984); Black: linker).

Ver todos los productos específicos de isoformas PROTACs :

Chemical Information

No. CAS 3027918-96-0
Appearance Solid
Peso molecular 830.31
Fòrmula C₃₉H₄₀ClN₉O₈S
Color Yellow to orange
SMILES

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCC(N4CCN(CC4)C5=CC=C(C(OC)=C5)NC6=NC=C(C(NC7=C(S(=O)(C(C)C)=O)C=CC=C7)=N6)Cl)=O)=CC=C3)=O)=O
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lidong Gong, et al. Discovery of a miniaturized PROTAC with potent activity and high selectivity. Bioorg Chem. 2023 Jul:136:106556. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
Referencias

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AP-1

High-Throughput Bioactive Compound Library

Ver todos los productos específicos de isoformas PROTACs

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

AP-1 Related Classifications

HY-169481 Related Classifications