Baptifoline
Based on 1 Customer Validation
Baptifoline is an alkaloid isolated from the rhizome of Caulophyllum thalictroides.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.0%
- No. CAS: 732-50-3
- Fòrmula: C15H20N2O2
- Peso molecular:260.33
-
Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Chemical Information
-
No. CAS 732-50-3
-
Appearance Solid
-
Peso molecular 260.33
-
Fòrmula C15H20N2O2
-
Color White to off-white
-
SMILES
O=C1N2C([C@@]3([H])CN(CC[C@@H](O)C4)[C@@]4([H])[C@]([H])(C3)C2)=CC=C1
-
Structure Classification
-
Initial Source
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
Ethanol : ≥ 50 mg/mL (192.06 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (4.80 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (4.80 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
-
Ficha de datos (272 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 3.8413 mL | 19.2064 mL | 38.4128 mL | 96.0320 mL |
| 5 mM | 0.7683 mL | 3.8413 mL | 7.6826 mL | 19.2064 mL | |
| 10 mM | 0.3841 mL | 1.9206 mL | 3.8413 mL | 9.6032 mL | |
| 15 mM | 0.2561 mL | 1.2804 mL | 2.5609 mL | 6.4021 mL | |
| 20 mM | 0.1921 mL | 0.9603 mL | 1.9206 mL | 4.8016 mL | |
| 25 mM | 0.1537 mL | 0.7683 mL | 1.5365 mL | 3.8413 mL | |
| 30 mM | 0.1280 mL | 0.6402 mL | 1.2804 mL | 3.2011 mL | |
| 40 mM | 0.0960 mL | 0.4802 mL | 0.9603 mL | 2.4008 mL | |
| 50 mM | 0.0768 mL | 0.3841 mL | 0.7683 mL | 1.9206 mL | |
| 60 mM | 0.0640 mL | 0.3201 mL | 0.6402 mL | 1.6005 mL | |
| 80 mM | 0.0480 mL | 0.2401 mL | 0.4802 mL | 1.2004 mL | |
| 100 mM | 0.0384 mL | 0.1921 mL | 0.3841 mL | 0.9603 mL |