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United States

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Referencia número: HY-103438

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BIBU1361

BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6.

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No. CAS: 793726-84-8
Fòrmula: C₂₂H₂₇ClFN₇
Peso molecular:443.95

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BIBU1361 Chemical Structure

No. CAS: 793726-84-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6^[1].

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Chemical Information

No. CAS 793726-84-8
Peso molecular 443.95
Fòrmula C₂₂H₂₇ClFN₇
SMILES

CCN(CC1CCN(C2=NC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=N2)CC1)CC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ruchi Ghildiyal, et, al. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog. 2013, 52,12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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BIBU1361

Ver todos los productos específicos de isoformas Akt

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

BIBU1361 Related Classifications

HY-103438 Related Classifications