CGP71683
CGP 71683 Free base serves as a powerful and highly selective non-peptide antagonist targeting the NPY Y(5) receptor, making it a valuable tool in obesity research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 192321-23-6
- Fòrmula: C26H29N5O2S
- Peso molecular:475.61
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Neuropeptide Y Receptor
More
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| COS-1 | IC50 |
1.3 nM
Compound: CGP-71683A (Trans)
|
Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 transiently expressed in COS-1 cells using [125I]PYY
Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 transiently expressed in COS-1 cells using [125I]PYY
|
[PMID: 15863317] |
| COS-1 | IC50 |
97 nM
Compound: CGP-71683A (Trans)
|
Inhibitory activity against constitutively activated human Alpha-2A adrenergic receptor transiently expressed in COS-1 cells using [3H]MK-912
Inhibitory activity against constitutively activated human Alpha-2A adrenergic receptor transiently expressed in COS-1 cells using [3H]MK-912
|
[PMID: 15863317] |
| HEK293 | IC50 |
3500 nM
Compound: CGP-71683A (Trans)
|
Inhibitory activity against mutated constitutively activated human Melanin concentrating hormone receptor 1 (CA-MCH-R1) stably expressed in HEK293 cells using [125I](Phe13, Tyr19) MCH
Inhibitory activity against mutated constitutively activated human Melanin concentrating hormone receptor 1 (CA-MCH-R1) stably expressed in HEK293 cells using [125I](Phe13, Tyr19) MCH
|
[PMID: 15863317] |
Chemical Information
-
No. CAS 192321-23-6
-
Peso molecular 475.61
-
Fòrmula C26H29N5O2S
-
SMILES
NC1=NC(NC[C@@H](CC2)CC[C@H]2CNS(=O)(C3=CC=CC4=CC=CC=C34)=O)=NC5=CC=CC=C51
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)