Clavanin A
Clavanin A is a peptide Antibiotic and membrane permeabilizer. Clavanin A permeabilizes cytoplasmic membranes and unilamellar lipid bilayers, and dissipates membrane potential. Clavanin A inserts into phospholipid monolayers via hydrophobic interactions under physiologically relevant surface pressures. Clavanin A exhibits antibacterial activity against Micrococcus flavus. Clavanin A can be used in studies related to Micrococcus flavus infection.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 185518-51-8
- Fòrmula: C131H184N34O27
- Peso molecular:2667.07
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Antibiotic
More
Actividad biológica
Descripciòn
In Vitro
Clavanin A (starting serial dilution at 500 µg/mL; 24 h) inhibits the growth of Micrococcus flavus (DSM 1790), with an MIC of 4.9 µM[1].
Clavanin A (0.23 µM) dissipates the membrane potential of intact Micrococcus flavus cells, with inhibition rates reaching 58% and 80% at the concentration of 0.23 µM in two independent experiments[1].
Clavanin A (1-5 µM; 2 min) permeabilizes DOPC large unilamellar vesicles (LUVs), triggering the release of low-molecular-weight carboxyfluorescein and high-molecular-weight FITC-dextran (9400 Da) in the micromolar concentration range, which indicates a non-specific membrane permeabilization mechanism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 185518-51-8
-
Peso molecular 2667.07
-
Fòrmula C131H184N34O27
-
Sequence
Val-Phe-Gln-Phe-Leu-Gly-Lys-Ile-Ile-His-His-Val-Gly-Asn-Phe-Val-His-Gly-Phe-Ser-His-Val-Phe
-
Sequence Shortening
VFQFLGKIIHHVGNFVHGFSHVF
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clavanin A Related Classifications
HY-P11180 Related Classifications
Powered by Bioz