Daurisoline-d5
Daurisoline-d5 is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C37H37D5N2O6
- Peso molecular:615.77
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 70553-76-3
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Peso molecular 615.77
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Fòrmula C37H37D5N2O6
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SMILES
OC1=C([2H])C2=C(C([2H])=C1OC)CCN(C)[C@@H]2CC3=CC([2H])=C(O)C(OC4=CC=C(C[C@H]5N(C)CCC6=C5C([2H])=C(OC)C(OC)=C6[2H])C=C4)=C3
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Synonyms
(R,R)-Daurisoline-d5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Liu Q, et al. Effect of daurisoline on HERG channel electrophysiological function and protein expression. J Nat Prod. 2012 Sep 28;75(9):1539-45. [Content Brief]
[2]. Wu MY, et al. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity. Oncotarget. 2017 Sep 8;8(44):77673-77684. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)