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Referencia número: HY-161888

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DCSM06

DCSM06 is an inhibitor for the bromodomain of SWI/SNF chromatin remodeling complexe SMARCA2 with an IC₅₀ of 9.7 μM

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No. CAS: 924855-67-4
Fòrmula: C₂₁H₂₈N₂O
Peso molecular:324.46

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DCSM06 Chemical Structure

No. CAS: 924855-67-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Cellular Effect
Chemical Information
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Actividad biológica

Descripciòn

DCSM06 is an inhibitor for the bromodomain of SWI/SNF chromatin remodeling complexe SMARCA2 with an IC₅₀ of 9.7 μM^[1]

Ver todos los productos específicos de isoformas SWI/SNF Complex :

Cellular Effect

Cell Line	Type	Value	Description	References
HGC-27	IC₅₀	4.22 μM Compound: 46	Cytotoxicity against human HGC27 cells assessed as reduction in cell viability after 72 hrs by Alamar blue assay Cytotoxicity against human HGC27 cells assessed as reduction in cell viability after 72 hrs by Alamar blue assay	[PMID: 30128079]

Chemical Information

No. CAS 924855-67-4
Peso molecular 324.46
Fòrmula C₂₁H₂₈N₂O
SMILES

CC(C=C1)=CC=C1COC2=CC=C(CNCC3CCNCC3)C=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Lu T, et al., Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay. Acta Pharmacol Sin. 2018 Sep;39(9):1544-1552. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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DCSM06

Ver todos los productos específicos de isoformas SWI/SNF Complex

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

DCSM06 Related Classifications

HY-161888 Related Classifications