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Referencia número: HY-180164

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DS79540454

DS79540454 is a HIF-PHD2 inhibitor with an IC₅₀ 0.26 μM. DS79540454 can be used in the research of renal anemia.

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No. CAS: 1462947-17-6
Fòrmula: C₂₂H₂₀N₄O₅
Peso molecular:420.42

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

DS79540454 Chemical Structure

No. CAS: 1462947-17-6

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Actividad biológica

Descripciòn

DS79540454 is a HIF-PHD2 inhibitor with an IC₅₀ 0.26 μM. DS79540454 can be used in the research of renal anemia^[1].

IC₅₀ & Target

IC₅₀: 0.26 μM (HIF-PHD2)^[1]

Ver todos los productos específicos de isoformas HIF/HIF Prolyl-Hydroxylase :

Chemical Information

No. CAS 1462947-17-6
Peso molecular 420.42
Fòrmula C₂₂H₂₀N₄O₅
SMILES

O=C(C1=CN=C(NC(CCC(O)=O)=O)N=C1O)NCC2=CC(C3=CC=CC=C3)=CC=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Fukuda T, et al. Discovery of DS79540454 via fragment-based drug discovery strategy: New scaffolds of hypoxia-inducible factor prolyl hydroxylase inhibitor. Bioorg Med Chem Lett. 2026 Feb 1;131:130476. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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DS79540454

Ver todos los productos específicos de isoformas HIF/HIF Prolyl-Hydroxylase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

DS79540454 Related Classifications

HY-180164 Related Classifications