Eberconazole
Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole has potential for the study of dermatophytosis.
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- No. CAS: 128326-82-9
- Fòrmula: C18H14Cl2N2
- Peso molecular:329.22
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Eberconazole (0.03-2 μg/mL, 7 days) exhibits significant antifungal activity against 200 strains of dermatophytes, with the strongest activity against Trichophyton rubrum and Trichophyton mentagrophytes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Experimentally induced cutaneous candidiasis guinea pig model[2]
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Dosage:1%-1.3% Eberconazole cream, approximately 1-1.3 g per animal
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Administration:Topical application, twice daily, for 6 days
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Result:Caused 90% of guinea pigs clinically recovered and lesions disappeared.
Chemical Information
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No. CAS 128326-82-9
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Peso molecular 329.22
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Fòrmula C18H14Cl2N2
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SMILES
ClC1=CC(CCC2=C(C3N4C=NC=C4)C=CC=C2)=C3C(Cl)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)