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Referencia número: HY-N3924

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Ganoderiol F

Name: Ganoderiol F
Brand: MedChemExpress
SKU: HY-N3924
Price: 180.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 99.85%
No. CAS: 114567-47-4
Fòrmula: C₃₀H₄₆O₃
Peso molecular:454.68

Almacenamiento:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Ganoderiol F Chemical Structure

No. CAS: 114567-47-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF S-180	IC₅₀	7.1 μg/mL Compound: 15	Cytotoxicity against mouse S180 cells Cytotoxicity against mouse S180 cells	[PMID: 23092389]
HEK293	EC₅₀	5 μM Compound: 14	Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay	[PMID: 22014750]
HeLa	IC₅₀	5 μM Compound: 15	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 23092389]
Hep 3B2	IC₅₀	25.3 μM Compound: 15	Cytotoxicity against human Hep3B cells Cytotoxicity against human Hep3B cells	[PMID: 23092389]
HepG2	IC₅₀	17 μM Compound: 15	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 23092389]
HepG2	IC₅₀	20.7 μM Compound: 2	Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24974349]
Huh-7	IC₅₀	8.5 μM Compound: 15	Cytotoxicity against human HuH7 cells Cytotoxicity against human HuH7 cells	[PMID: 23092389]
K562	IC₅₀	4 μM Compound: 15	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 23092389]
K562	IC₅₀	54.9 μM Compound: 22	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 26287401]
Lewis lung carcinoma cell line	IC₅₀	2 μg/mL Compound: 15	Cytotoxicity against mouse LLC cells Cytotoxicity against mouse LLC cells	[PMID: 23092389]
PC-3	IC₅₀	79.5 μM Compound: 22	Cytotoxicity against human PC3 cells by MTT method Cytotoxicity against human PC3 cells by MTT method	[PMID: 26287401]
RAW264.7	IC₅₀	36 μM Compound: 7	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method	[PMID: 23357630]
T47D	IC₅₀	3 μg/mL Compound: 15	Cytotoxicity against human T47D cells Cytotoxicity against human T47D cells	[PMID: 23092389]

Chemical Information

No. CAS 114567-47-4
Appearance Solid
Peso molecular 454.68
Fòrmula C₃₀H₄₆O₃
Color White to off-white
SMILES

C[C@]1(CC[C@]2([H])[C@H](C)CC/C=C(CO)/CO)C(C3=CC[C@@]12C)=CC[C@](C(C)4C)([H])[C@@]3(CCC4=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Microorganisms
Ganoderma amboinense
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Chang UM, et al. Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells. Life Sci. 2006;79(12):1129-1139. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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