Glutaurine
Based on 1 Customer Validation
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia.
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- Pureza: 95.15%
- No. CAS: 56488-60-9
- Fòrmula: C7H14N2O6S
- Peso molecular:254.26
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Almacenamiento:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Glutaurine (100~3000 ug/kg; i.p.) significantly reduces T3 blood levels in a dose-dependent manner, but does not significantly raise T4 blood levels[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CFY male rats (170~250g)[2]
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Dosage:1, 10, 20 or 50 μg/rat
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Administration:P.o.
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Result:Significantly restored the latency of entry in both the 24 and 48 h tests at the dose of 50 μg/rat.
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Animal Model:Fischer 344 rats[3]
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Dosage:100~3000 ug/kg
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Administration:I.p.
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Result:Significantly reduced T3 blood levels in a dose-dependent manner, but did not significantly raise T4 blood levels.
Chemical Information
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No. CAS 56488-60-9
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Appearance Solid
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Peso molecular 254.26
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Fòrmula C7H14N2O6S
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(NCCS(=O)(O)=O)=O)=O
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Synonyms
Litoralon
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvente y solubilidad
H2O : 125 mg/mL (491.62 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Balázs M, et al. Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine. Neuropeptides. 1988;12(2):55-58. [Content Brief]
[2]. Feuer L, et al. Effect of glutaurine, a newly discovered parathyroid hormone on rat thymus cultures. Acta Morphol Acad Sci Hung. 1978;26(2):87-94. [Content Brief]
[3]. Baskin S, et al. The effect of glutaurine on thyroid hormones in the rat. Neuropeptides. 1987;9(1):45-50. [Content Brief]
[4]. Uemura S, et al. Gamma-glutamyltaurine has potent and long-lasting antiepileptic action as demonstrated by intra-amygdaloid injection in amygdala-kindled rats. Brain Res. 1992;594(2):347-350. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.9330 mL | 19.6649 mL | 39.3298 mL | 98.3246 mL |
| 5 mM | 0.7866 mL | 3.9330 mL | 7.8660 mL | 19.6649 mL | |
| 10 mM | 0.3933 mL | 1.9665 mL | 3.9330 mL | 9.8325 mL | |
| 15 mM | 0.2622 mL | 1.3110 mL | 2.6220 mL | 6.5550 mL | |
| 20 mM | 0.1966 mL | 0.9832 mL | 1.9665 mL | 4.9162 mL | |
| 25 mM | 0.1573 mL | 0.7866 mL | 1.5732 mL | 3.9330 mL | |
| 30 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2775 mL | |
| 40 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4581 mL | |
| 50 mM | 0.0787 mL | 0.3933 mL | 0.7866 mL | 1.9665 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6387 mL | |
| 80 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2291 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3933 mL | 0.9832 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glutaurine Related Classifications
HY-106608 Related Classifications
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