Koenimbine
Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer.
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- No. CAS: 21087-98-9
- Fòrmula: C19H19NO2
- Peso molecular:293.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
1.2 μM
Compound: 13
|
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
|
[PMID: 23376010] |
| DU-145 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| HCT-116 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| HeLa | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| HepG2 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| OVCAR-3 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| PA-1 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 34838335] |
Chemical Information
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No. CAS 21087-98-9
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Peso molecular 293.36
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Fòrmula C19H19NO2
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SMILES
CC1=CC2=C(NC3=C2C=C(C=C3)OC)C4=C1OC(C)(C=C4)C
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Koenimbine Related Classifications
HY-W727999 Related Classifications
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