mCPX
mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV+ gastric cancer cells via the hypoxia pathway (HIF‑1α). mCPX is applicable to research related to EBV-positive gastric cancer.
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- No. CAS: 1351572-56-9
- Fòrmula: C14H19NO3
- Peso molecular:249.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
mCPX induces EBV lytic cycle in SNU719 and AGSBX1 EBV+ gastric cancer cell lines with activity comparable to CPX, and has significantly greater resistance to iron-mediated inactivation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Parmacokinetics
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1351572-56-9
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Peso molecular 249.31
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Fòrmula C14H19NO3
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SMILES
O=C(C)ON(C(C1CCCCC1)=CC(C)=C2)C2=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mCPX Related Classifications
HY-183552 Related Classifications
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