ML350
ML350 (CYM50202) is a highly potent OPRK1 antagonist with selectivity and broad biological applications. With IC50 values of 9-16 nM, ML350 shows high selectivity for OPRK1, with selectivity of 219-382-fold and 20-35-fold relative to OPRD1 and OPRM1, respectively. ML350 exhibited favorable characteristics in in vivo pharmacokinetic analysis, including high passive membrane permeability and moderate human plasma protein binding. Extensive screening of ML350 against multiple ion channels, receptors, and transporters showed that it does not have adverse off-target effects.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1565852-90-5
- Fòrmula: C18H26BrN3O3
- Peso molecular:412.32
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Endogenous Metabolite
More
Actividad biológica
Chemical Information
-
No. CAS 1565852-90-5
-
Peso molecular 412.32
-
Fòrmula C18H26BrN3O3
-
SMILES
O=C(OC)C1=CC(Br)=CN=C1N2C[C@@H]([C@H](CC2)NC3CCCCC3)O
-
Synonyms
CYM50202
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML350 Related Classifications
HY-116163 Related Classifications
Powered by Bioz