MRS4833
MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC50 of 5.92 nM for hP2Y14R and an IC50 of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model.
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- No. CAS: 2801627-78-9
- Fòrmula: C30H24F3NO3
- Peso molecular:503.51
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Ver todos los productos específicos de isoformas P2Y Receptor
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Actividad biológica
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hP2Y14R 5.92 nM (IC50) |
mP2Y14R 4.8 nM (IC50) |
Chemical Information
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No. CAS 2801627-78-9
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Peso molecular 503.51
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Fòrmula C30H24F3NO3
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SMILES
O[C@@]1(C2=CC=C(C3=CC(C(O)=O)=CC4=C3C=CC(C5=CC=C(C=C5)C(F)(F)F)=C4)C=C2)[C@]6([H])C[C@@]1([H])CNC6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRS4833 Related Classifications
HY-167855 Related Classifications
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