Mtb-IN-2
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
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- No. CAS: 2861190-30-7
- Fòrmula: C17H12N2O4
- Peso molecular:308.29
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>1000 μM
Compound: 10c
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Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability
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[PMID: 37423128] |
Chemical Information
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No. CAS 2861190-30-7
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Peso molecular 308.29
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Fòrmula C17H12N2O4
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SMILES
O=C(NC1=CC(O)=C(C(O)=O)C=C1)C2=NC3=C(C=C2)C=CC=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mtb-IN-2 Related Classifications
HY-149346 Related Classifications
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