NMS-P953
NMS-P953 (compound 28) is an orally active JAK2 inhibitor (IC50=0.008 μM) with antitumor activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1403679-33-3
- Fòrmula: C16H11ClF3N5O
- Peso molecular:381.74
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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JAK2 0.008 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
1.47 μM
Compound: 28
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Antiproliferative activity against human A2780 cells after 72 hrs by Cell Titer-Glo assay
Antiproliferative activity against human A2780 cells after 72 hrs by Cell Titer-Glo assay
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[PMID: 25009002] |
Chemical Information
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No. CAS 1403679-33-3
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Peso molecular 381.74
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Fòrmula C16H11ClF3N5O
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SMILES
O=C(C1=C(C2=CC(C(F)(F)F)=CC=C2Cl)NC(C3=NC(N)=NC=C3)=C1)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NMS-P953 Related Classifications
HY-129679 Related Classifications
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