NNRT-IN-2
NNRT-IN-2 (compound 7w) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains. NNRT-IN-2 inhibits HIV-1 reverse transcriptase with an EC50 of 22 nM. NNRT-IN-2 is insensitive to CYP and hERG and has good safety and pharmacokinetic characteristics.
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- No. CAS: 2999794-78-2
- Fòrmula: C19H14F3N5O3
- Peso molecular:417.34
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
EC50: 22 nM (HIV Reverse Transcriptase)[1]
Chemical Information
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No. CAS 2999794-78-2
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Peso molecular 417.34
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Fòrmula C19H14F3N5O3
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SMILES
CN1C(NN=C1CN2C=CC(C(F)(F)F)=C(C2=O)OC3=C4C=CN=CC4=CC=C3)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)