SNIPER(ABL)-033
SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM (ABL inhibitor: HY-15814; ABL inhibitor activity control: HY-131178; E3 ligase ligand: HY-128808; linker: HY-130500; E3 ligase ligand + linker: HY-128819).
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- No. CAS: 2222354-18-7
- Fòrmula: C61H73F3N10O9S2
- Peso molecular:1211.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 2222354-18-7
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Peso molecular 1211.42
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Fòrmula C61H73F3N10O9S2
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SMILES
CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCOC6=CC(C(C7=CSC([C@H]8N(C([C@H](C9CCCCC9)NC([C@H](C)NC)=O)=O)CCC8)=N7)=O)=CC=C6)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SNIPER(ABL)-033 Related Classifications
HY-111871 Related Classifications
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