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Referencia número: HY-184040

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TDO-IN-3

TDO-IN-3 (compound 20) is an IDO1/TDO inhibitor with IC₅₀ values of 4.12 and 0.12 μM, respectively.

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No. CAS: 2490673-04-4
Fòrmula: C₁₄H₁₈BrN₃O
Peso molecular:324.22

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

TDO-IN-3 Chemical Structure

No. CAS: 2490673-04-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

TDO-IN-3 (compound 20) is an IDO1/TDO inhibitor with IC₅₀ values of 4.12 and 0.12 μM, respectively^[1].

IC₅₀ & Target

^[1]

IDO1

4.12 μM (IC₅₀)

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO) :

Chemical Information

No. CAS 2490673-04-4
Peso molecular 324.22
Fòrmula C₁₄H₁₈BrN₃O
SMILES

BrC1=CC(NCC2C(CCCC2)O)=C3C(NN=C3)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Ning XL, et al. X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease. J Med Chem. 2021;64(12):8303-8332. [Content Brief]

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Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TDO-IN-3

Ver todos los productos específicos de isoformas Indoleamine 2,3-Dioxygenase (IDO)

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