Tofacitinib-d3
Tofacitinib-d3 (Tasocitinib-d3) is deuterium labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C16H17D3N6O
- Peso molecular:315.39
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 477600-75-2
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Peso molecular 315.39
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Fòrmula C16H17D3N6O
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SMILES
O=C(N1C[C@@H]([C@@H](CC1)C)N(C([2H])([2H])[2H])C2=C3C(NC=C3)=NC=N2)CC#N
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Synonyms
Tasocitinib-d3; CP-690550-d3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)