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Vixtimotamab

(Synonyms: AMV-564; TandAb T564)
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Based on 1 Customer Validation

Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human CD33 and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML).

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  • Pureza: 97.29%
  • No. CAS: 2243775-32-6
  • Peso molecular:103.14 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vixtimotamab
  • Experimental Validation Results for Vixtimotamab
  • Experimental Validation Results for Vixtimotamab
  • Experimental Validation Results for Vixtimotamab
  • Experimental Validation Results for Vixtimotamab
  • Vixtimotamab Chemical Structure
    Vixtimotamab Chemical Structure
No. CAS: 2243775-32-6
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Vixtimotamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    [V-kappa-VH-V-lambda-VH']-noncovalent dimer (tandem diabody)

  • 1/16

    Immobilized Vixtimotamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 4.95 ng/mL.

  • 1/16

    Immobilized Vixtimotamab can bind Human Siglec-3/CD33 Protein (ECD, His Tag). The EC50 for this effect is 4.95 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Vixtimotamab (HY-P99958). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 THP-1 cells labeling CD33 with Vixtimotamab (HY-P99958, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Vixtimotamab Chemical Structure
    1/16
  • Vixtimotamab
  • Immobilized Vixtimotamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 4.95 ng/mL.
  • Immobilized Vixtimotamab can bind Human Siglec-3/CD33 Protein (ECD, His Tag). The EC50 for this effect is 4.95 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Vixtimotamab (HY-P99958). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 THP-1 cells labeling CD33 with Vixtimotamab (HY-P99958, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • [V-kappa-VH-V-lambda-VH']-noncovalent dimer (tandem diabody)