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Vudalimab

(Synonyms: XmAb20717)
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Based on 1 Customer Validation

Vudalimab (XmAb20717) is a bispecific antibody that binds PD-1 and CTLA-4. Vudalimab preferentially binds to cells co-expressing PD-1 and CTLA-4 and blocks inhibitory checkpoint signaling to promote T cell activation. Vudalimab can be used for research in metastatic castration-resistant prostate cancer (including high-risk disease) and gynecological malignancies.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza : ≥99.0%
  • No. CAS: 2329669-72-7
  • Peso molecular:144.5 kDa
  • Almacenamiento:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vudalimab
  • Experimental Validation Results for Vudalimab
  • Experimental Validation Results for Vudalimab
  • Vudalimab Chemical Structure
    Vudalimab Chemical Structure
No. CAS: 2329669-72-7
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Vudalimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Vudalimab (anti-CTLA4) (HY-P99166). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow Cytometry analysis of THP-1 cells labelling PDCD1 (red) with Vudalimab (anti-PDCD1) (HY-P99166). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Vudalimab Chemical Structure
    1/16
  • Vudalimab
  • Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Vudalimab (anti-CTLA4) (HY-P99166). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow Cytometry analysis of THP-1 cells labelling PDCD1 (red) with Vudalimab (anti-PDCD1) (HY-P99166). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3