YTH-IN-2
YTH-IN-2 is a YTH domain inhibitor of YTHDC2 with an IC50 of 16.84 μM. YTH-IN-2 can serve as a lead compound for discovering efficient, selective, and cell-active small-molecule inhibitors of YTHDC2.
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- No. CAS: 86886-76-2
- Fòrmula: C14H12ClNO2
- Peso molecular:261.70
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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YTHDC2 16.84 μM (IC50) |
YTH-IN-2 (H3) (30 min compound-protein incubation; 2 h post-probe addition incubation) inhibits recombinant human GST-tagged YTHDC2 YTH-domain protein binding to FAM-labeled m6A-mRNA with an IC50 of 16.84 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 86886-76-2
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Peso molecular 261.70
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Fòrmula C14H12ClNO2
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SMILES
O=C(CC1=CC=CC=C1)NC2=CC(Cl)=CC=C2O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YTH-IN-2 Related Classifications
HY-181117 Related Classifications
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