ZC0101
ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2541604-52-6
- Fòrmula: C17H15N3O2
- Peso molecular:293.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
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IDO1 0.084 μM (IC50) |
TrxR 7.98 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
0.55 μM
Compound: 41; ZC0101
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Cytotoxicity against human HCT-116 incubated for 24 hrs by CCK-8 assay
Cytotoxicity against human HCT-116 incubated for 24 hrs by CCK-8 assay
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[PMID: 35696861] |
In Vivo
Chemical Information
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No. CAS 2541604-52-6
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Peso molecular 293.32
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Fòrmula C17H15N3O2
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SMILES
O=C1C=CCCN1C(/C=C/C2=CC=CC=C2C3=CNC=N3)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZC0101 Related Classifications
HY-147772 Related Classifications
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