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Referencia número: HY-186108

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ZY38

ZY38 is a SaClpP agonist that activates SaClpP-mediated α-casein hydrolysis with an EC₅₀ of 1.52 μM. ZY38 exhibits bactericidal activity against Staphylococcus aureus. ZY38 is applicable to studies related to Staphylococcus aureus infections, such as peritonitis.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₈H₃₅F₃N₄O₃
Peso molecular:532.60

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

ZY38 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vitro

ZY38 activates SaClpP-mediated α-casein hydrolysis in vitro with an EC₅₀ of 1.52 ± 0.2 μM^[1].
ZY38 inhibits the growth of S. aureus Newman in vitro with an MIC of 0.25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Peso molecular 532.60
Fòrmula C₂₈H₃₅F₃N₄O₃
SMILES

O=C(N(CCC1=O)[C@@]([H])(CN2CC3=C4C=CC=CC4=C(C)C=C3)N1[C@@H]([C@@H](C)CC)C2=O)NCCCC(F)(F)F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhang T, et al. Structure-Guided Development of ClpP Agonists with Potent Therapeutic Activities against Staphylococcus aureus Infection. J Med Chem. 2025 Jan 23;68(2):1810-1823. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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