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Cat. No.: HY-123381

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Gemopatrilat

(Synonyms: BMS-189921)

Gemopatrilat (BMS-189921) is an orally active vasopeptidase inhibitor with IC₅₀ value of 12 nM. Gemopatrilat can be used in studies of hypertension and congestive heart failure.

For research use only. We do not sell to patients.

CAS No.: 160135-92-2
Formula: C₁₉H₂₆N₂O₄S
Molecular Weight:378.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Gemopatrilat Chemical Structure

CAS No.: 160135-92-2

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Sample (0.1mg)

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(In Japan)

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Gemopatrilat (BMS-189921) is an orally active vasopeptidase inhibitor with IC₅₀ value of 12 nM. Gemopatrilat can be used in studies of hypertension and congestive heart failure^[1].

IC₅₀ & Target

ACE

12 nM (IC₅₀)

Chemical Information

CAS No. 160135-92-2
Molecular Weight 378.49
Formula C₁₉H₂₆N₂O₄S
SMILES

O=C(O)CN1C(C)(C)CCC[C@H](NC([C@@H](S)CC2=CC=CC=C2)=O)C1=O
Synonyms

BMS-189921
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robl JA, et al. Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides. J Med Chem. 1999 Jan 28;42(2):305-11. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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