GNA13 - G protein subunit alpha 13 Gene

Also Known as G13; HG1N

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10672

About GNA13

Cytogenetic location: 17q24.1 Genomic coordinates (GRCh38): 17:65,009,289-65,056,740 (from NCBI)

This gene has 2 transcripts (splice variants), 310 orthologues and 15 paralogues. Ubiquitous expression in bone marrow (RPKM 46.2), lymph node (RPKM 22.6) and 24 other tissues.

Summary

Predicted to enable D5 Dopamine Receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in several processes, including Rho protein signal transduction; activation of Phospholipase D activity; and multicellular organism aging. Predicted to act upstream of or within several processes, including branching involved in blood vessel morphogenesis; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GNA13 Products (2)

mRNA Protein Name
NM_001282425.2 NP_001269354.1 guanine nucleotide-binding protein subunit alpha-13 isoform 2
NM_006572.6 NP_006563.2 guanine nucleotide-binding protein subunit alpha-13 isoform 1

GNA13 Protein Structure

G-alpha

G-alpha: G-protein alpha subunit (22 - 366)

  • 0
  • 100
  • 200
  • 300
  • 377 a.a.
Protein Preferred Names Protein Names

guanine nucleotide-binding protein subunit alpha-13

  • g alpha-13

GNA13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GNA13 Q14344 CXCR5 Homo sapiens P32302
Anti Bait CoIP
23773523
Intra
GNA13 Q14344 ARHGEF1 Homo sapiens Q92888
Anti Tag CoIP
12681510
Cross: Cross-species interaction Intra: Intraspecies interaction

GNA13 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83133 GNA13 Antibody (YA2878) WB, IHC-P Human
HY-P83133A GNA13 Antibody (YA2878)(PBS only) WB, IHC-P Human

Related Diseases

Diseases Alias
St2 Diffuse Large B-Cell Lymphoma

  • St2 Dlbcl

  • Doid:0081068
Ezb Diffuse Large B-Cell Lymphoma

  • Ezb Dlbcl

  • Doid:0081065
Diffuse Large B-Cell Lymphoma Activated B-Cell Type

  • Dlbcl Abc Type
Mcd Diffuse Large B-Cell Lymphoma

  • Mcd Dlbcl

  • Doid:0081066
High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit

  • Hgbl-Dh/Th

  • High Grade B-Cell Lymphoma With Myc And Bcl2 Or Bcl6 Rearrangements

  • High Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement
Dendritic Cell Deficiency
Primary Mediastinal B-Cell Lymphoma

  • Large Cell Lymphoma Of The Mediastinum

  • Mediastinal Diffuse Large-Cell Lymphoma With Sclerosis

  • Primary Mediastinal Clear Cell Lymphoma Of B-Cell Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05531 GNA13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20938 Gna13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27455 Gna13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GNA13 MGD MGI:95768
Canis familiaris GNA13 VGNC VGNC:41298
Macaca mulatta GNA13 VGNC VGNC:73087
Felis catus GNA13 VGNC VGNC:62615
Rattus norvegicus GNA13 RGD RGD:1310221
Bos taurus GNA13 VGNC VGNC:29446
Others GNA13 NCBI