2. Gene
  3. USP39 - ubiquitin specific peptidase 39 Gene

USP39 - ubiquitin specific peptidase 39 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as 65K; SAD1; CGI-21; HSPC332; SNRNP65

Gene ID: 10713 | Gene type: protein coding

About USP39

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:85,602,861-85,649,283 (from NCBI)

This gene has 20 transcripts (splice variants), 206 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 14.6), placenta (RPKM 13.8) and 25 other tissues.

Summary

Predicted to enable thiol-dependent Deubiquitinase and zinc ion binding activity. Involved in spliceosomal complex assembly. Located in nucleoplasm. Part of U4/U6 x U5 tri-snRNP complex. [provided by Alliance of Genome Resources, Apr 2022]

USP39 Products(5)

mRNA Protein Name
NM_001256725.2 NP_001243654.1 U4/U6.U5 tri-snRNP-associated protein 2 isoform 1
NM_001256726.2 NP_001243655.1 U4/U6.U5 tri-snRNP-associated protein 2 isoform 2
NM_001256727.2 NP_001243656.1 U4/U6.U5 tri-snRNP-associated protein 2 isoform 3
NM_001256728.2 NP_001243657.1 U4/U6.U5 tri-snRNP-associated protein 2 isoform 4
NM_006590.4 NP_006581.2 U4/U6.U5 tri-snRNP-associated protein 2 isoform 1

USP39 Protein Structure

zf-UBP

zf-UBP: Zn-finger in ubiquitin-hydrolases and other protein (129 - 185)

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (225 - 550)

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  • 565 a.a.
Protein Preferred Names Protein Names

U4/U6.U5 tri-snRNP-associated protein 2

SAD1 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15550 USP39 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus USP39 RGD RGD:1308103
Bos taurus USP39 VGNC VGNC:36728
Mus musculus USP39 MGD MGI:107622
Canis familiaris USP39 VGNC VGNC:48194
Macaca mulatta USP39 VGNC VGNC:79227
Felis catus USP39 VGNC VGNC:66885