ZBTB6 - zinc finger and BTB domain containing 6 Gene

Also Known as ZID; ZNF482

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10773

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in lymph node (RPKM 5.7), thyroid (RPKM 5.5) and 25 other tissues.

ZBTB6 Products (1)

mRNA Protein Name
NM_006626.6 NP_006617.1 zinc finger and BTB domain-containing protein 6
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZBTB6 Q15916 SUMO1P1 Homo sapiens G2XKQ0 25416956
Intra
ZBTB6 Q15916 RNF4 Homo sapiens P78317 32296183
Intra
ZBTB6 Q15916 RNF4 Homo sapiens P78317 32296183
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 32296183
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 25416956
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 32296183
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 25416956
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 32296183
Intra
ZBTB6 Q15916 ZBTB26 Homo sapiens Q9HCK0 25416956
Intra
ZBTB6 Q15916 PLEKHF2 Homo sapiens Q9H8W4 32296183
Intra
ZBTB6 Q15916 PLEKHF2 Homo sapiens Q9H8W4 32296183
Intra
ZBTB6 Q15916 PLEKHF2 Homo sapiens Q9H8W4 32296183
Intra
ZBTB6 Q15916 SUMO1 Homo sapiens P63165 25416956
Intra
ZBTB6 Q15916 FAM9A Homo sapiens Q8IZU1 32296183
Intra
ZBTB6 Q15916 FAM9A Homo sapiens Q8IZU1 32296183
Intra
ZBTB6 Q15916 FAM9A Homo sapiens Q8IZU1 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction