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UTP14A - UTP14A small subunit processome component Gene

Also Known as Utp14; NYCO16; SDCCAG16; dJ537K23.3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 10813

About UTP14A

Cytogenetic location: Xq26.1 Genomic coordinates (GRCh38): X:129,906,164-129,929,752 (from NCBI)

This gene has 4 transcripts (splice variants), 230 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 5.9), appendix (RPKM 5.8) and 25 other tissues.

Summary

This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

UTP14A Products (2)

mRNA	Protein	Name
NM_001166221.2	NP_001159693.1	U3 small nucleolar RNA-associated protein 14 homolog A isoform 2
NM_006649.4	NP_006640.2	U3 small nucleolar RNA-associated protein 14 homolog A isoform 1

UTP14A Protein Structure

Utp14

0
200
400
600
771 a.a.

Protein Preferred Names	Protein Names
U3 small nucleolar RNA-associated protein 14 homolog A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A

UTP14A Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	UTP14A	Q9BVJ6	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	CAMK2A	Homo sapiens	Q9UQM7	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	CAMK2A	Homo sapiens	Q9UQM7	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	CAMK2A	Homo sapiens	Q9UQM7	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	APLP2	Homo sapiens	Q06481-5	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	APLP2	Homo sapiens	Q06481-5	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	APLP2	Homo sapiens	Q06481-5	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	GADD45G	Homo sapiens	O95257	Y2H	15383276
Intra	UTP14A	Q9BVJ6	GADD45G	Homo sapiens	O95257	Y2H	21900206
Intra	UTP14A	Q9BVJ6	A2M	Homo sapiens	P01023	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	A2M	Homo sapiens	P01023	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	A2M	Homo sapiens	P01023	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	ATXN10	Homo sapiens	Q9UBB4	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	ATXN10	Homo sapiens	Q9UBB4	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	ATXN10	Homo sapiens	Q9UBB4	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	BLMH	Homo sapiens	Q13867	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	BLMH	Homo sapiens	Q13867	Y2H Pooling	32814053
Intra	UTP14A	Q9BVJ6	BLMH	Homo sapiens	Q13867	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	LDOC1	Homo sapiens	O95751	Y2H Pooling	16189514
Intra	UTP14A	Q9BVJ6	LDOC1	Homo sapiens	O95751	Y2H Array	31515488
Intra	UTP14A	Q9BVJ6	SMYD1	Homo sapiens	Q8NB12	Y2H	23455924
Intra	UTP14A	Q9BVJ6	CSNK1D	Homo sapiens	P48730-2	Validated Y2H	32814053
Intra	UTP14A	Q9BVJ6	CSNK1D	Homo sapiens	P48730-2	Y2H Array	32814053
Intra	UTP14A	Q9BVJ6	CSNK1D	Homo sapiens	P48730-2	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Bowen-Conradi Syndrome	BWCNS Bowen Hutterite Syndrome Bowen-Conradi Hutterite Syndrome Bowen Syndrome, Hutterite Type Bowen Hutterite Syndrome, Formerly Hutterite Syndrome Bowen Syndrome Hutterite Type Fetal Growth Retardation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15575	UTP14A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	UTP14A	RGD	RGD:1359313
Mus musculus	UTP14A	MGD	MGI:1919804
Macaca mulatta	UTP14A	VGNC	VGNC:103882
Others	UTP14A	NCBI