2. Gene
  3. DBF4 - DBF4 zinc finger Gene

DBF4 - DBF4 zinc finger Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ASK; CHIF; DBF4A; ZDBF1

Gene ID: 10926 | Gene type: protein coding

About DBF4

Cytogenetic location: 7q21.12 Genomic coordinates (GRCh38): 7:87,876,493-87,909,553 (from NCBI)

This gene has 8 transcripts (splice variants), 210 orthologues and 1 paralogue. Biased expression in testis (RPKM 30.3), bone marrow (RPKM 10.3) and 9 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

DBF4 Products(4)

mRNA Protein Name
NM_001318060.2 NP_001304989.1 protein DBF4 homolog A isoform 2
NM_001318061.2 NP_001304990.1 protein DBF4 homolog A isoform 3
NM_001318062.2 NP_001304991.1 protein DBF4 homolog A isoform 4
NM_006716.4 NP_006707.1 protein DBF4 homolog A isoform 1

DBF4 Protein Structure

zf-DBF

zf-DBF: DBF zinc finger (290 - 334)

  • 0
  • 200
  • 400
  • 600
  • 674 a.a.
Protein Preferred Names Protein Names

protein DBF4 homolog A

DBF4 homolog

Related Diseases

Diseases Alias
Meier-Gorlin Syndrome 1

Meier-Gorlin Syndrome

Ear, Patella, Short Stature Syndrome

Microtia, Absent Patellae, Micrognathia Syndrome

MGORS1

Eps

Ear-Patella-Short Stature Syndrome

Ear Patella Short Stature Syndrome

Microtia Absent Patellae Micrognathia Syndrome

Meier-Gorlin Syndrome, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143432 Cdc7-IN-18 Inhibitor / Unkown
HY-RS03543 DBF4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DBF4 MGD MGI:1351328
Canis familiaris DBF4 VGNC VGNC:39780
Macaca mulatta DBF4 VGNC VGNC:71645
Rattus norvegicus DBF4 RGD RGD:1305854
Bos taurus DBF4 VGNC VGNC:27887
Felis catus DBF4 VGNC VGNC:61345