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HNRNPUL1 - heterogeneous nuclear ribonucleoprotein U like 1 Gene

Also Known as E1BAP5; E1B-AP5; HNRPUL1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 11100

About HNRNPUL1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,262,557-41,307,787 (from NCBI)

This gene has 21 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 41.5), ovary (RPKM 40.7) and 25 other tissues.

Summary

This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016]

HNRNPUL1 Products (5)

mRNA	Protein	Name
NM_001301016.3	NP_001287945.1	heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform e
NM_001321208.2	NP_001308137.1	heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_001321211.2	NP_001308140.1	heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_007040.6	NP_008971.2	heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform a
NM_144732.5	NP_653333.1	heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	11513728	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	12489984	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in nucleus	IDA IDA: Inferred from direct assay	11513728	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HNRNPUL1 Protein Structure

SAP

SPRY

AAA_33

0
200
400
600
800
856 a.a.

Protein Preferred Names	Protein Names
heterogeneous nuclear ribonucleoprotein U-like protein 1	E1B 55kDa associated protein 5

HNRNPUL1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	HNRNPUL1	Q9BUJ2	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Array	32296183
Intra	HNRNPUL1	Q9BUJ2	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Prey Pooling	32296183
Intra	HNRNPUL1	Q9BUJ2	VPS37C	Homo sapiens	A5D8V6	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	VPS37C	Homo sapiens	A5D8V6	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	SF3B4	Homo sapiens	Q15427	Y2H	22365833
Intra	HNRNPUL1	Q9BUJ2	SF3B4	Homo sapiens	Q15427	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	SF3B4	Homo sapiens	Q15427	Y2H Array	25416956
Intra	HNRNPUL1	Q9BUJ2	PIAS2	Homo sapiens	O75928-2	Y2H Prey Pooling	32296183
Intra	HNRNPUL1	Q9BUJ2	PIAS2	Homo sapiens	O75928-2	Y2H Array	32296183
Intra	HNRNPUL1	Q9BUJ2	HNRNPF	Homo sapiens	P52597	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	HNRNPF	Homo sapiens	P52597	Y2H Array	29892012
Intra	HNRNPUL1	Q9BUJ2	HNRNPF	Homo sapiens	P52597	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	HNRNPF	Homo sapiens	P52597	Y2H	22365833
Intra	HNRNPUL1	Q9BUJ2	BRD7	Homo sapiens	Q9NPI1	Anti Bait CoIP	12489984
Intra	HNRNPUL1	Q9BUJ2	BRD7	Homo sapiens	Q9NPI1	Y2H	12489984
Intra	HNRNPUL1	Q9BUJ2	BRD7	Homo sapiens	Q9NPI1	Pull Down	12489984
Intra	HNRNPUL1	Q9BUJ2	BRD7	Homo sapiens	Q9NPI1	Fluorescence	12489984
Intra	HNRNPUL1	Q9BUJ2	RBM4B	Homo sapiens	Q9BQ04	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	SORBS3	Homo sapiens	O60504	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	MAPK1IP1L	Homo sapiens	Q8NDC0	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	MAPK1IP1L	Homo sapiens	Q8NDC0	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H Array	31515488
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H Array	25416956
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H Array	32296183
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H	21516116
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H Array	29892012
Intra	HNRNPUL1	Q9BUJ2	WWP2	Homo sapiens	O00308	Y2H Prey Pooling	32296183
Intra	HNRNPUL1	Q9BUJ2	KLHDC7B	Homo sapiens	Q96G42	Y2H Array	32296183
Intra	HNRNPUL1	Q9BUJ2	KLHDC7B	Homo sapiens	Q96G42	Y2H Prey Pooling	32296183
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Y2H Prey Pooling	25416956
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Validated Y2H	25416956
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Y2H Prey Pooling	32296183
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Y2H Array	25416956
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Y2H Array	32296183
Intra	HNRNPUL1	Q9BUJ2	DZIP3	Homo sapiens	Q86Y13	Y2H Array	29892012

Cross: Cross-species interaction Intra: Intraspecies interaction

HNRNPUL1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82803	E1B AP5 Antibody (YA2548)	WB, IHC-F, IHC-P, ICC/IF	Human
HY-P82803A	E1B AP5 Antibody (YA2548)(PBS only)	WB, IHC-F, IHC-P, ICC/IF	Human

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06279	HNRNPUL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	HNRNPUL1	VGNC	VGNC:73401
Bos taurus	HNRNPUL1	VGNC	VGNC:50035
Rattus norvegicus	HNRNPUL1	RGD	RGD:1307456
Mus musculus	HNRNPUL1	MGD	MGI:2443517
Felis catus	HNRNPUL1	VGNC	VGNC:62828
Canis familiaris	HNRNPUL1	VGNC	VGNC:53724
Others	HNRNPUL1	NCBI