DZIP3 - DAZ interacting zinc finger protein 3 Gene

Also Known as UURF2; PPP1R66; hRUL138

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9666

About DZIP3

Cytogenetic location: 3q13.13 Genomic coordinates (GRCh38): 3:108,589,510-108,694,840 (from NCBI)

This gene has 6 transcripts (splice variants), 191 orthologues and 4 paralogues. Broad expression in testis (RPKM 21.6), brain (RPKM 12.1) and 21 other tissues.

Summary

Enables several functions, including Phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Involved in protein polyubiquitination. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DZIP3 Products (1)

mRNA Protein Name
NM_014648.4 NP_055463.1 E3 ubiquitin-protein ligase DZIP3

DZIP3 Protein Structure

zf-RING_2

zf-RING_2: Ring finger domain (1147 - 1188)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1208 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase DZIP3

  • DAZ interacting protein 3, zinc finger

DZIP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DZIP3 Q86Y13 HNRNPUL1 Homo sapiens Q9BUJ2
Validated Y2H
32296183
Intra
DZIP3 Q86Y13 UBE2E2 Homo sapiens Q96LR5
Y2H Array
19549727
Intra
DZIP3 Q86Y13 FBXO17 Homo sapiens Q96EF6
Validated Y2H
32296183
Intra
DZIP3 Q86Y13 TIAL1 Homo sapiens Q01085
Anti Tag CoIP
28514442
Intra
DZIP3 Q86Y13 TIAL1 Homo sapiens Q01085
Anti Tag CoIP
33961781
Intra
DZIP3 Q86Y13 ARHGAP32 Homo sapiens A7KAX9
Y2H Array
25416956
Intra
DZIP3 Q86Y13 ARHGAP32 Homo sapiens A7KAX9
Y2H Prey Pooling
25416956
Intra
DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Y2H Prey Pooling
25416956
Intra
DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Validated Y2H
25416956
Intra
DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Y2H Array
25416956
Intra
DZIP3 Q86Y13 ZCCHC10 Homo sapiens Q8TBK6
Validated Y2H
25416956
Intra
DZIP3 Q86Y13 ZCCHC10 Homo sapiens Q8TBK6
Y2H Array
31515488
Intra
DZIP3 Q86Y13 ZNF24 Homo sapiens P17028
Validated Y2H
25416956
Intra
DZIP3 Q86Y13 ZNF24 Homo sapiens P17028
Y2H Array
31515488
Intra
DZIP3 Q86Y13 RBM4B Homo sapiens Q9BQ04
Y2H Array
25416956
Intra
DZIP3 Q86Y13 RBM4B Homo sapiens Q9BQ04
Validated Y2H
25416956
Intra
DZIP3 Q86Y13 CEP63 Homo sapiens Q96MT8
Validated Y2H
25416956
Intra
DZIP3 Q86Y13 CEP63 Homo sapiens Q96MT8
Y2H Array
25416956
Intra
DZIP3 Q86Y13 TOLLIP Homo sapiens Q9H0E2
Anti Tag CoIP
21903422
Intra
DZIP3 Q86Y13 GTF2H2C Homo sapiens Q6P1K8
Y2H Prey Pooling
25416956
Intra
DZIP3 Q86Y13 ATXN1 Homo sapiens P54253
Y2H
16713569
Intra
DZIP3 Q86Y13 ZNF765 Homo sapiens Q7L2R6
Y2H Prey Pooling
25416956
Intra
DZIP3 Q86Y13 ZNF765 Homo sapiens Q7L2R6
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04109 DZIP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DZIP3 VGNC VGNC:61693
Rattus norvegicus DZIP3 RGD RGD:1563278
Bos taurus DZIP3 VGNC VGNC:28285
Mus musculus DZIP3 MGD MGI:1917433
Macaca mulatta DZIP3 VGNC VGNC:72019
Canis familiaris DZIP3 VGNC VGNC:40163
Others DZIP3 NCBI