Hcn2 - hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114244

Summary

Enables PDZ domain binding activity and molecular adaptor activity. Involved in several processes, including aging; cellular response to aldosterone; and response to cisplatin. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of dermatitis; meningitis; and visual epilepsy. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and Sodium Channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Hcn2 Products (1)

mRNA Protein Name
NM_053684.2 NP_446136.1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Protein Preferred Names Protein Names

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-18940 Cilobradine / Phase 1

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160505 RO-275 Inhibitor 99.95% Unkown
HY-13422A Zatebradine Antagonist 99.27% Unkown
HY-13422 Zatebradine hydrochloride Antagonist 99.87% Unkown
HY-186056 HCN2-IN-3 Inhibitor / Unkown
HY-186057 HCN2-IN-5 Inhibitor / Unkown
HY-186058 HCN2-IN-6 Inhibitor / Unkown
HY-186059 HCN2 modulator-4 Inhibitor / Unkown
HY-186059A HCN2 modulator-5 Inhibitor / Unkown
HY-186060 HCN2 modulator-6 Inhibitor / Unkown
HY-186061 HCN2-IN-4 Inhibitor / Unkown
HY-186061A HCN2 modulator-8 Inhibitor / Unkown
HY-186062 HCN-IN-1 / Unkown
HY-186065 HCN2-IN-1 Inhibitor / Unkown
HY-186066 HCN2-IN-2 Inhibitor / Unkown
HY-RS06047 HCN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18617 Hcn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25103 Hcn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hcn2 NCBI NCBI:610