Sf1 - splicing factor 1 Gene

Also Known as Zfp162

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117855

Summary

Predicted to enable identical protein binding activity and mRNA binding activity. Involved in negative regulation of smooth muscle cell proliferation. Predicted to be located in nuclear body. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Used to study ischemia. Orthologous to human SF1 (splicing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sf1 Products (2)

mRNA Protein Name
NM_001110793.1 NP_001104263.1 splicing factor 1 isoform 1
NM_058210.2 NP_478117.2 splicing factor 1 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
11748220 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor 1

  • zinc finger protein 162

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0627 Metformin 99.98% Yes
HY-17471A Metformin hydrochloride 99.98% Yes
HY-17471AR Metformin hydrochloride (Standard) 99.97% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0627A Metformin (glycinate) / Phase 3

Pre-clinical Phase

Bioactive Molecules (28)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115613 ML-180 Inhibitor 99.96% Unkown
HY-153736 NSC 194308 99.86% Unkown
HY-131445 RJW100 Activator 99.93% Unkown
HY-107404 SID 7969543 Inhibitor 99.12% Unkown
HY-117738 Benarthin Inhibitor 95.79% Unkown
HY-131445B RR-RJW100 99.73% Unkown
HY-134462A RJW103 TFA Agonist / Unkown
HY-134462 RJW103 Agonist 98.71% Unkown
HY-168545 SF-1 Ligand 99.50% Unkown
HY-B0627S Metformin-d6 98.16% Unkown
HY-128207 SID7970631 Inhibitor 98.30% Unkown
HY-129359 PDP-Pfp 98.27% Unkown
HY-131445A SS-RJW100 99.91% Unkown
HY-402601 Desethyl-SID 7969543 Control 98.83% Unkown
HY-129372 PDdB-Pfp / Unkown
HY-148259 SF-1 antagonist-1 Antagonist / Unkown
HY-167960 BrAc-Galactose-Sar-N-Me-alanine-DM1 / Unkown
HY-RS09553 NR5A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12756 SF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14606 TM4SF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-155168 Iso-RJW100 Inhibitor / Unkown
HY-RS16877 Sf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17509 Nr5a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19821 Tm4sf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23319 Sf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23966 Nr5a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26317 Tm4sf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0627S1 Metformin-13C2 hydrochloride / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991187 Anti-TM4SF1 Antibody (AGX-A07) Inhibitor 99.01% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sf1 NCBI NCBI:7536