UBXN2B - UBX domain protein 2B Gene
Also Known as p37
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 137886
Summary
Predicted to enable ubiquitin binding activity. Involved in several processes, including negative regulation of protein localization to centrosome; positive regulation of mitotic centrosome separation; and protein unfolding. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and spindle pole centrosome. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in brain (RPKM 9.6), thyroid (RPKM 8.2) and 25 other tissues.
UBXN2B Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001077619.2 | NP_001071087.1 | UBX domain-containing protein 2B isoform 1 |
| NM_001330535.2 | NP_001317464.1 | UBX domain-containing protein 2B isoform 2 |
| NM_001363181.1 | NP_001350110.1 | UBX domain-containing protein 2B isoform 3 |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in establishment of mitotic spindle orientation |
IGI
IGI: Inferred from genetic interaction
|
23649807 | GOA |
| involved in negative regulation of protein localization to centrosome |
IGI
IGI: Inferred from genetic interaction
|
23649807 | GOA |
| involved in positive regulation of mitotic centrosome separation |
IGI
IGI: Inferred from genetic interaction
|
23649807 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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UBXN2B Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
UBXN2B | Q14CS0 | VAT1L | Homo sapiens | Q9HCJ6 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | VAT1L | Homo sapiens | Q9HCJ6 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | VAT1L | Homo sapiens | Q9HCJ6 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | VCF1 | Homo sapiens | Q969W3 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | VCF1 | Homo sapiens | Q969W3 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | VCF1 | Homo sapiens | Q969W3 | 33961781 | |
|
Intra
|
UBXN2B | Q14CS0 | VCF1 | Homo sapiens | Q969W3 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | UBXN6 | Homo sapiens | Q9BZV1 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | UBXN6 | Homo sapiens | Q9BZV1 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | UBXN6 | Homo sapiens | Q9BZV1 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | XAF1 | Homo sapiens | Q6GPH4 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | XAF1 | Homo sapiens | Q6GPH4 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | XAF1 | Homo sapiens | Q6GPH4 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | MEOX1 | Homo sapiens | P50221 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | PAX5 | Homo sapiens | Q02548 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | PAX5 | Homo sapiens | Q02548 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 33961781 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 28514442 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 29997244 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 29997244 | |
|
Intra
|
UBXN2B | Q14CS0 | VCP | Homo sapiens | P55072 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | NGLY1 | Homo sapiens | Q96IV0 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | NGLY1 | Homo sapiens | Q96IV0 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | NGLY1 | Homo sapiens | Q96IV0 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | NGLY1 | Homo sapiens | Q96IV0 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | INCA1 | Homo sapiens | Q0VD86 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | INCA1 | Homo sapiens | Q0VD86 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | INCA1 | Homo sapiens | Q0VD86 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | INCA1 | Homo sapiens | Q0VD86 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | INCA1 | Homo sapiens | Q0VD86 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | PIN1 | Homo sapiens | Q13526 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | PIN1 | Homo sapiens | Q13526 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | PAX6 | Homo sapiens | P26367 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | PAX6 | Homo sapiens | P26367 | 32296183 | |
|
Intra
|
UBXN2B | Q14CS0 | CRX | Homo sapiens | O43186 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | CRX | Homo sapiens | O43186 | 25416956 | |
|
Intra
|
UBXN2B | Q14CS0 | CRX | Homo sapiens | O43186 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction