Hpd - 4-hydroxyphenylpyruvic acid dioxygenase Gene

Also Known as Fla; Flp; Laf; Hppd; 4HPPD

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15445

Summary

Predicted to enable 4-hydroxyphenylpyruvate dioxygenase activity. Predicted to be involved in tyrosine catabolic process. Predicted to act upstream of or within L-phenylalanine catabolic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in alimentary system; liver; musculature; and respiratory system. Used to study tyrosinemia type III. Human ortholog(s) of this gene implicated in hawkinsinuria and tyrosinemia type III. Orthologous to human HPD (4-hydroxyphenylpyruvate dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Hpd Products (1)

mRNA Protein Name
NM_008277.3 NP_032303.1 4-hydroxyphenylpyruvate dioxygenase

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31537781 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

4-hydroxyphenylpyruvate dioxygenase

  • 4-hydroxyphenylpyruvic acid oxidase

  • F liver antigen

  • F protein

  • HPPDase

  • f Alloantigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (18)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W010040 4-​Hydroxyphenylpyruvic acid 98.63% Unkown
HY-W087027 Maleimide-NOTA 99.69% Unkown
HY-13495 ML281 98.04% Unkown
HY-131183 PROTAC PD-1/PD-L1 degrader-1 Inhibitor 99.52% Unkown
HY-135767 Bicyclopyrone Inhibitor 99.95% Unkown
HY-W010040R 4-Hydroxyphenylpyruvic acid (Standard) 96.44% Unkown
HY-174830 GJ19 Inhibitor 98.02% Unkown
HY-P2477 Human PD-L1 inhibitor IV Inhibitor 99.92% Unkown
HY-P2478 Human PD-L1 inhibitor V Inhibitor 98.70% Unkown
HY-P2474 Human PD-L1 inhibitor I 99.22% Unkown
HY-P2478A Human PD-L1 inhibitor V TFA Inhibitor / Unkown
HY-130625 PD-1/PD-L1-IN 6 Inhibitor / Unkown
HY-155740 PD-1/PD-L1-IN-32 Inhibitor / Unkown
HY-168080 PD-1/PD-L1-IN-51 Inhibitor / Unkown
HY-175294 PD-L1/Nampt-IN-1 Inhibitor / Unkown
HY-RS06335 HPD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17066 Hpd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23510 Hpd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpd NCBI NCBI:3242