2. Gene
  3. Il1b - interleukin 1 beta Gene

Il1b - interleukin 1 beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Il-1b; IL-1beta

Gene ID: 16176 | Gene type: protein coding

About Il1b

Chromosome 2: 129,206,490-129,213,059 reverse strand.GRCm39:CM000995.3

This gene has 3 transcripts (splice variants), 233 orthologues, 6 paralogues and is associated with 31 phenotypes. Broad expression in spleen adult (RPKM 1.3), lung adult (RPKM 1.) and 19 other tissues.

Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by Caspase 1. The encoded protein plays a role in thymocyte proliferation and is involved in the inflammatory response. [provided by RefSeq, Aug 2015]

Il1b Products(1)

mRNA Protein Name
NM_008361.4 NP_032387.1 interleukin-1 beta

Il1b Protein Structure

IL1_propep

IL1_propep: pfam02394 (0 - 101)

IL1

IL1: smart00125 (119 - 264)

  • 0
  • 100
  • 200
  • 269 a.a.
Protein Preferred Names Protein Names

interleukin-1 beta

IL-1 beta

Recombinant Il1b Proteins

Cat. No. Product Name Accession Purity
HY-P7073 IL-1 beta Protein, Mouse P10749 (V118-S269) ≥95%
HY-P7073A IL-1 beta Protein, Mouse (CHO) P10749 (V118-S269) ≥95%
HY-P70437 IL-1beta Protein, Mouse P10749(V118-S269) ≥95%
HY-P700187AF Animal-Free IL-1 beta Protein, Mouse (His) P10749 (V118-S269) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-141852 STAMBP-IN-1 Inhibitor 98.37% Unkown
HY-111662 Fc 11a-2 Inhibitor / Unkown
HY-147105 LRH-1 modulator-1 Modulator / Unkown
HY-162168 Anti-inflammatory agent 71 / Unkown
HY-P1117 MMK1 / Unkown
HY-P1117A MMK1 TFA / Unkown
HY-RS06716 IL1B Human Pre-designed siRNA Set A / Unkown
HY-RS06717 Il1b Mouse Pre-designed siRNA Set A / Unkown
HY-RS06718 Il1b Rat Pre-designed siRNA Set A / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99139 Anti-Mouse IL-1b Antibody (B122) Inhibitor 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1b NCBI NCBI:3553
Canis familiaris Il1b NCBI NCBI:403974
Felis catus Il1b NCBI NCBI:768274
Macaca fascicularis Il1b NCBI NCBI:102119749
Susscrofa domestica Il1b NCBI
Leporidae Il1b NCBI
Rattus norvegicus Il1b NCBI NCBI:24494
Macaca mulatta Il1b NCBI NCBI:704701