Cblb - Cbl proto-oncogene B Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171136

Summary

Enables protein kinase binding activity. Involved in response to gravity; response to hormone; and signal transduction. Located in membrane raft. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and type 1 diabetes mellitus. Orthologous to human CBLB (Cbl proto-oncogene B). [provided by Alliance of Genome Resources, Apr 2022]

Cblb Products (1)

mRNA Protein Name
NM_133601.1 NP_598285.1 E3 ubiquitin-protein ligase CBL-B

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein kinase binding IPI
IPI: Inferred from physical interaction
14531861 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
14715702 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19546888 RGD
involved in response to gravity IEP
IEP: Inferred from expression pattern
14715702 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
16984225 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase CBL-B

  • Cas-Br-M (murine) ecotropic retroviral transforming sequence b

  • Cas-Br-M (murine) ectropic retroviral transforming sequence b

  • Casitas B-lineage lymphoma b

  • Cbl proto-oncogene B, E3 ubiquitin protein ligase

  • Cbl proto-oncogene, E3 ubiquitin protein ligase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (34)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141432 NX-1607 Inhibitor 99.87% Unkown
HY-136339 Cbl-b-IN-1 Inhibitor 99.66% Unkown
HY-155815 MS9715 99.48% Unkown
HY-155120 Cbl-b-IN-5 Inhibitor 99.05% Unkown
HY-156766 Cbl-b-IN-10 Inhibitor 98.85% Unkown
HY-155477 Cbl-b-IN-15 Inhibitor 99.78% Unkown
HY-156765 Cbl-b-IN-9 Inhibitor 98.55% Unkown
HY-161977 Cbl-b-IN-26 Inhibitor 99.81% Unkown
HY-156769 Cbl-b-IN-13 Inhibitor 98.46% Unkown
HY-141431 Cbl-b-IN-2 Inhibitor / Unkown
HY-156768 Cbl-b-IN-12 Inhibitor / Unkown
HY-156762 Cbl-b-IN-6 Inhibitor / Unkown
HY-156763 Cbl-b-IN-7 Inhibitor / Unkown
HY-156764 Cbl-b-IN-8 Inhibitor / Unkown
HY-156767 Cbl-b-IN-11 Inhibitor / Unkown
HY-158171 Cbl-b-IN-17 Inhibitor / Unkown
HY-158173 Cbl-b-IN-19 Inhibitor / Unkown
HY-159608 PROTAC Cbl-b-IN-1 Degrader / Unkown
HY-163194 Cbl-b-IN-16 Inhibitor / Unkown
HY-164133 SM00465 Inhibitor / Unkown
HY-169005 Cbl-b-IN-27 Inhibitor / Unkown
HY-173311 Cbl-b-IN-28 / Unkown
HY-179575 Cbl-b-IN-29 / Unkown
HY-179617 Cbl-b-IN-30 Inhibitor / Unkown
HY-183293 Cbl-b-IN-32 Inhibitor / Unkown
HY-183997 Cbl-b-IN-33 / Unkown
HY-184236 Cbl-b-IN-34 Inhibitor / Unkown
HY-P11479 Cbl-b-IN-31 Inhibitor / Unkown
HY-P11481 FITC-Acp-RpYTPEP-NH2 Ligand / Unkown
HY-RS01997 CBLB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08508 MMAB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-141432G NX-1607 (GMP) Inhibitor / Unkown
HY-RS17948 Cblb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24419 Cblb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cblb NCBI NCBI:868