2. Gene
  3. Pou5f1 - POU domain, class 5, transcription factor 1 Gene

Pou5f1 - POU domain, class 5, transcription factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Oct3; Oct4; Otf3; Otf4; NF-A3; Oct-3; Oct-4; Otf-3; Otf-4; Otf3g; Oct3/4; Oct-3/4; Otf3-rs7

Gene ID: 18999 | Gene type: protein coding

About Pou5f1

Chromosome 17: 35,816,915-35,821,669 forward strand.GRCm39:CM001010.3

This gene has 6 transcripts (splice variants), 331 orthologues, 16 paralogues and is associated with 4 phenotypes. Biased expression in testis adult (RPKM 4.) and ovary adult (RPKM 1.5).

Summary

The protein encoded by this gene belongs to the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein plays a key role in embryonic development and stem cell pluripotency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Pou5f1 Products(2)

mRNA Protein Name
NM_013633.3 NP_038661.2 POU domain, class 5, transcription factor 1 isoform 1
NM_001252452.1 NP_001239381.1 POU domain, class 5, transcription factor 1 isoform 2

Pou5f1 Protein Structure

POU

POU: smart00352 (130 - 204)

Homeobox

Homeobox: pfam00046 (225 - 278)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

POU domain, class 5, transcription factor 1

octamer-binding protein 3

octamer-binding protein 4

octamer-binding transcription factor 3

octamer-binding transcription factor 4 alternative

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10907 POU5F1 Human Pre-designed siRNA Set A / Unkown
HY-RS10908 Pou5f1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS10909 Pou5f1 Rat Pre-designed siRNA Set A / Unkown
HY-RS10910 POU5F1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou5f1 NCBI NCBI:5460