Star - steroidogenic acute regulatory protein Gene

Also Known as stARD1; D8Ertd419e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20845

Summary

Predicted to enable Cholesterol binding activity. Acts upstream of or within cellular lipid metabolic process; glucocorticoid metabolic process; and regulation of steroid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including adrenal gland; extraembryonic component; and reproductive system. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Orthologous to human STAR (steroidogenic acute regulatory protein). [provided by Alliance of Genome Resources, Apr 2022]

Star Products (1)

mRNA Protein Name
NM_011485.5 NP_035615.2 steroidogenic acute regulatory protein, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cholesterol binding IDA
IDA: Inferred from direct assay
12011452 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular lipid metabolic process IMP
IMP: Inferred from mutant phenotype
9326645 MGI
acts upstream of or within glucocorticoid metabolic process IMP
IMP: Inferred from mutant phenotype
9326645 MGI
acts upstream of or within regulation of steroid biosynthetic process IDA
IDA: Inferred from direct assay
7961770 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
7961770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

steroidogenic acute regulatory protein, mitochondrial

  • START domain-containing protein 1

  • luteinizing hormone-induced protein

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12502A Efonidipine hydrochloride monoethanolate Inhibitor 99.83% Unkown
HY-12502 Efonidipine Inhibitor 99.88% Unkown
HY-12502AR Efonidipine hydrochloride monoethanolate (Standard) Inhibitor / Unkown
HY-12502B Efonidipine hydrochloride Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15483 DY131 99.72% Unkown
HY-Y0740 4-Methoxybenzaldehyde 99.80% Unkown
HY-W1048851B 4-Arm-PEG10000-Maleimide 97.0% Unkown
HY-134462 RJW103 Agonist 98.71% Unkown
HY-W073128 Perfluorotetradecanoic acid 98.0% Unkown
HY-D2348 ACE / Unkown
HY-143656 SH379 / Unkown
HY-161384 WJM-715 Inhibitor / Unkown
HY-N12102 Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside Inhibitor / Unkown
HY-N12136 1α-Hydroxy-3-deoxypseudoanisatin / Unkown
HY-P10780 RFRP-3 (mouse) 98.82% Unkown
HY-RS02193 CD163L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05921 GUCY2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13875 STAR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W750726 7,8,7’,8’-Tetradehydroastaxanthin / Unkown
HY-Y0740S 4-Methoxybenzaldehyde-d1 / Unkown
HY-Y0740S1 4-Methoxybenzaldehyde-d3 / Unkown
HY-RS18153 Star Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24627 Star Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W721611 Terbucarb / Unkown
HY-Y0740S2 4-Methoxybenzaldehyde-d2 / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992132 Solaprubart Inhibitor 99.59% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Star NCBI NCBI:6770